We have a Asp.net solution (having c# and vb.net code with Ajax). Was running fine in Test and when moved to Prod , it started giving JavaScript errors. And happens for many pages When checked server got the following error.

Event code: 3005
Event message: An unhandled exception has occurred.
Event time: 31/03/2014 13:48:10
Event time (UTC): 31/03/2014 12:48:10
Event ID: 37dd3345a5964cf19ac94b2c05976457
Event sequence: 3
Event occurrence: 1
Event detail code: 0
Application information: Application domain: /LM/W3SVC/7862/Root-4-130407436897106054 Trust level: Full Application Virtual Path: / Application Path: D:\MSINetData\WWW\MT\ Machine name: P01TSDES01
Process information: Process ID: 28140 Process name: w3wp.exe Account name: NT AUTHORITY\NETWORK SERVICE
Exception information: Exception type: MethodAccessException Exception message: Attempt to access method System.Management.Instrumentation.InstrumentedAttribute..ctor(System.String) in violation of security transparency rules failed. at System.RuntimeMethodHandle.CheckLinktimeDemands(IRuntimeMethodInfo method, RuntimeModule module, Boolean isDecoratedTargetSecurityTransparent) at System.Reflection.CustomAttribute.GetCustomAttributes(RuntimeModule decoratedModule, Int32 decoratedMetadataToken, Int32 pcaCount, RuntimeType attributeFilterType, Boolean mustBeInheritable, IList derivedAttributes, Boolean isDecoratedTargetSecurityTransparent) at System.Reflection.CustomAttribute.GetCustomAttributes(RuntimeAssembly assembly, RuntimeType caType) at System.Reflection.RuntimeAssembly.GetCustomAttributes(Boolean inherit) at System.Web.UI.AssemblyCache.GetAjaxFrameworkAssemblyAttribute(Assembly assembly) at System.Web.UI.ScriptManager.get_DefaultAjaxFrameworkAssembly() at System.Web.UI.ScriptManager..ctor() at ASP.repository_projectcontact_aspx.__BuildControlToolkitScriptManager1() at ASP.repository_projectcontact_aspx.__BuildControlContent2(Control __ctrl) at System.Web.UI.CompiledTemplateBuilder.InstantiateIn(Control container) at System.Web.UI.MasterPage.InstantiateInContentPlaceHolder(Control contentPlaceHolder, ITemplate template) at ASP.master_mt_master.__BuildControlMTMContent() at ASP.master_mt_master.__BuildControlform1() at ASP.master_mt_master.__BuildControlTree(master_mt_master __ctrl) at ASP.master_mt_master.FrameworkInitialize() at System.Web.UI.UserControl.InitializeAsUserControlInternal() at System.Web.UI.MasterPage.CreateMaster(TemplateControl owner, HttpContext context, VirtualPath masterPageFile, IDictionary contentTemplateCollection) at System.Web.UI.Page.get_Master() at System.Web.UI.Page.ApplyMasterPage() at System.Web.UI.Page.PerformPreInit() at System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint) Request information: Request URL: Request path: /Repository/ProjectContact.aspx User host address: User: Is authenticated: False Authentication Type: Thread account name: P01TSDES01\MX-PAR
Thread information: Thread ID: 5 Thread account name: P01TSDES01\MX-PAR Is impersonating: False Stack trace: at System.RuntimeMethodHandle.CheckLinktimeDemands(IRuntimeMethodInfo method, RuntimeModule module, Boolean isDecoratedTargetSecurityTransparent) at System.Reflection.CustomAttribute.GetCustomAttributes(RuntimeModule decoratedModule, Int32 decoratedMetadataToken, Int32 pcaCount, RuntimeType attributeFilterType, Boolean mustBeInheritable, IList derivedAttributes, Boolean isDecoratedTargetSecurityTransparent) at System.Reflection.CustomAttribute.GetCustomAttributes(RuntimeAssembly assembly, RuntimeType caType) at System.Reflection.RuntimeAssembly.GetCustomAttributes(Boolean inherit) at System.Web.UI.AssemblyCache.GetAjaxFrameworkAssemblyAttribute(Assembly assembly) at System.Web.UI.ScriptManager.get_DefaultAjaxFrameworkAssembly() at System.Web.UI.ScriptManager..ctor() at ASP.repository_projectcontact_aspx.__BuildControlToolkitScriptManager1() at ASP.repository_projectcontact_aspx.__BuildControlContent2(Control __ctrl) at System.Web.UI.CompiledTemplateBuilder.InstantiateIn(Control container) at System.Web.UI.MasterPage.InstantiateInContentPlaceHolder(Control contentPlaceHolder, ITemplate template) at ASP.master_mt_master.__BuildControlMTMContent() at ASP.master_mt_master.__BuildControlform1() at ASP.master_mt_master.__BuildControlTree(master_mt_master __ctrl) at ASP.master_mt_master.FrameworkInitialize() at System.Web.UI.UserControl.InitializeAsUserControlInternal() at System.Web.UI.MasterPage.CreateMaster(TemplateControl owner, HttpContext context, VirtualPath masterPageFile, IDictionary contentTemplateCollection) at System.Web.UI.Page.get_Master() at System.Web.UI.Page.ApplyMasterPage() at System.Web.UI.Page.PerformPreInit() at System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint)
Custom event details:
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1 Answer

Seems like you're having security issue. asp:ScriptManager is a typical cause for this error. Maybe you should try adding this to your web.config:

<system.web> <trust level="Full"/>
</system.web>

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